µ-Slide I Luer 3D

Product Description

A µ-Slide with one channel and three wells for culturing cells on a 3D gel matrix with defined flow

Create a perfusable cell monolayer on a gel matrix for various flow and shear stress applications

Establish and image endothelial barriers under in vivo -like conditions—no artificial filters or membranes

Easy handling: samples are placed into the open wells; perfusion is applied after closing the wells

Applications

Culture of adherent cells on a 3D gel matrix under flow conditions

Transendothelial migration studies under flow conditions

Establishment and microscopic read-out of endothelial barrier assays (without any artificial membrane)

Simulation of blood vessels with endothelial cell culture on a soft substrate

Long-term or short-term cell culture perfusion experiments with defined shear stress and optimal nutrient supply into 3D structures

Apical-basal cell polarity assays

Cell barrier model assays with apical-basal gradients

Cell boundary assays without filters or porous membranes

Rolling and adhesion assays using leukocytes

Inflammation studies

Transport studies