ACTINOMYCIN D
ACT001.5
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CAS number: [50-76-0]
(From Streptomyces species)
- 20°C
Antibiotic. Inhibits cell growth by complexing with DNA and interfering with RNA synthesis. At high dose of 2 μg/ml, it inhibits the transcription of all RNA species.
At a lower dose of 40 ng/ml it inhibits the synthesis of rRNA. Used in cell culture as a selection agent.
C62H86N12O16
MW: 1255.43
Purity (HPLC) > 95.0%
Appearance: red powder
Solubility: DMSO, ethanol
Working concentrations: 0.01 to 2 μg/ml